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KMID : 0363219920300010131
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Korean Journal of Dermatology
1992 Volume.30 No. 1 p.131 ~ p.134
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A Case of Prokeratosis Induced by Topical PUVA in a Vitiligo patient
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Abstract
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A 20-year-old female, who had been treated with topical PUVA therapy for her vitiligo. developed characteristic skin lesions of disseminated superficial actinic porokeratosis (DSAP). All of her three sisters had vitiligo and had been treated with
topical PUVA, but only one developed DSAP lesion. Her mother had had DSAP lesions on exposed areas for 20 years.
DSAP shows an autosomal dominant mode of inheritance. and is charaterized by multiple dark brownish keratotic papaules surrounded by slightly elevated border. The exacerbation of the lesion by exposure to UV lign indicates that the regulating
gene
for
DSAP is related to sunlight.
Herein we reported a case of DSAP induced by topical PUVA therapy in one patient during management of familial vitiligo in 3 sisters. (Kor J Dermatol 1992:30 (1) : 131-134)
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